王溪西安交通大学医学部 公共卫生学院 劳动卫生与环境卫生学系，讲师
联系方式：
地址: 西安市雁塔西路76号，西安交通大学医学部公共卫生学院
邮编：710061；
E-mail: wn18andlife@xjtu.edu.cn
教育经历:
2006年9月-2011年7月：陕西中医药大学公共卫生系预防医学
2011年9月-2016年9月：西安交通大学医学部公共卫生学院
工作经历:
2016年10月-至今：：西安交通大学医学院公共卫生学院讲师
研究方向:
大骨节病临床诊断、病因发病机制与防治研究；环境与基因相关疾病研究。
参加国内外会议：
参加国际、国内学术会议5次，分别在2014年、2016年中韩国际硒元素研讨会（英文报告，并被评为国际会议优秀报告）与第九次全国地方病学术会议进行大会报告，在“一带一路”全球健康国际研讨会暨2017年中华预防医学会全球卫生分会学术年会进行分会场报告（英文报告）。
主持及参与基金：
主持国家自然科学基金青年项目，中国博士后科学基金面上项目，陕西省自然科学基金青年项目和校基本科研业务费，参与3项国家自然科学基金项目，其中担任“大骨节病硒代谢系统与硒蛋白的分子功能研究”政府间科技合作-中韩合作项目分题负责人。
科研成果与代表性论著：
目前已发表SCI论文26篇，其中第一作者/通讯作者10篇，共同第一作者5篇，参与论文11篇。参与编写大骨节病论著2部，一部为英国皇家社会化学出版社（Royal Society of Chemistry, RSC）出版的《Selenium》专著中“硒与大骨节病”章节内容。一部为人民卫生出版社出版的《Endemic Disease in China》专著中“大骨节病”章节内容。
发表论文目录：
[1]. Xi Wang, Pan Zhang, Yujie Ning, Lei Yang, Fangfang Yu, Xiong Guo*. Serum and Hair Zinc Levels in Patients with Endemic Osteochondropathy in China: A Meta-analysis, Biological Trace Element Research, 2018; 181(2):227-233.
[2]. Xi Wang, Yujie Ning,Lei Yang, Fangfang Yu, Xiong Guo*. Zinc: the Other Suspected Environmental Factor in Kashin-Beck Disease in Addition to Selenium. Biological Trace Element Research, 2017; 179(2):178-184.
[3]. Xi Wang, Yujie Ning, Pan Zhang, Lei Yang, Yingting Wang, Xiong Guo*, Chondrocytes Damage Induced by T-2 Toxin via Wnt/β-Catenin Signaling Pathway is Involved in the Pathogenesis of an Endemic Osteochondropathy, Kashin-Beck Disease, Experimental Cell Research, 2017; 361(1):141-148.
[4]. Xi Wang, Yujie Ning, Bing Zhou, Lei Yang, Yingting Wang, Xiong Guo*, Integrated Bioinformatics Analysis of the Osteoarthritis‑Associated microRNA Expression Signature, Molecular Medicine Reports, 2017; 17(1):1833-1838.
[5]. Xi Wang, Yujie Ning, Lei Yang, Huan Liu, Cuiyan Wu, Sen Wang, Xiong Guo*, Diagnostic Value of Circulating microRNAs for Osteosarcoma in Asian Populations: A Meta-analysis, Clinical and Experimental Medicine, 2017;17(2):175-183.
[6]. Xi Wang, Yujie Ning, Wuhong Tan, Hanjie Yu, Zheng Li, Xiong Guo*. Population-based Comparative Analysis of Differentially Expressed Genes between Kashin-Beck Disease GradeⅠandⅡ. Scandinavian Journal of Rheumatology. 2016;45(3):230-235.
[7]. Xi Wang, Yujie Ning, Feng Zhang, Fangfang Yu, Wuhong Tan, Yanxia Lei, Cuiyan Wu, Jingjing Zheng, Sen Wang, Hanjie Yu, Zheng Li, Mikko J. Lammi, Xiong Guo*. Gene Expression Signature in Endemic Osteoarthritis by Microarray Analysis. International Journal of Molecular Sciences. 2015; 16: 11465-11481.
[8]. Xi Wang, Yujie Ning, Xiong Guo*. Integrative Meta-analysis of Differentially Expressed Genes in Osteoarthritis using Microarray Technology. Molecular Medicine Reports. 2015; 12(3):3439-45.
[9]. Xi Wang, Shuang Wang, Shulan He, Feng Zhang, Wuhong Tan, Yanxia Lei, Hanjie Yu, Zheng Li, Yujie Ning, Youzhang Xiang, Xiong Guo*. Comparing Gene Expression Profiles of Kashin-Beck and Keshan Disease Occurring within the Same Endemic Areas of China. Science China Life Sciences. 2013; 56(9):797-803.
[10]. Lei Yang, Jianping Zhang, Guanghui Zhao, Cuiyan Wu, Yujie Ning,Xi Wang*, Mikko J. Lammi, Xiong Guo*. Gene Expression Profiles and Molecular Mechanism of Cultured Human Chondrocytes’ Exposure to T-2 Toxin and Deoxynivalenol. Toxicon, 2017; 140:38-44.
[11]. Yujie Ning,Xi Wang(co-first author), Pan Zhang, Skalny V. Anatoly, N. Tejo Prakash, Cheng Li, Rong Zhou, Mikko Lammi, Feng Zhang, Xiong Guo. Imbalance of Dietary Nutrients and Associated Differentially Expressed Genes and Pathways May Play Important Roles in Juvenile Kashin-Beck Disease. Journal of Trace Elements in Medicine and Biology, 2018, Epub ahead of print.
[12]. Yujie Ning,Xi Wang(co-first author), Pan Zhang, Amin Liu, Xin Qi, Meidan Liu, Xiong Guo. Dietary Exosome‑miR‑23b May be a Novel Therapeutic Measure for Preventing Kashin‑Beck Disease. Experimental and Therapeutic Medicine. 2018, Accept.
[13]. Yujie Ning,Xi Wang(co-first author), Xiong Guo*, Pan Zhang, Pengfei Qu, Feng Zhang, Sen Wang, Yanxia Lei, Mikko Lammi, Nutrients Other than Selenium Are Important for Promoting Children's Health in Kashin-Beck Disease Areas. Biological Trace Element Research, Epub ahead of print, 2017.
[14]. Yujie Ning,Xi Wang(co-first author), Sen Wang, Xiong Guo*. Comparative Analysis on Signaling Pathways of Peripheral Blood Mononuclear Cells between Kashin-Beck Disease and Osteoarthritis. Experimental and Therapeutic Medicine. 2016;12(6):4077-4084.
[15]. Yujie Ning,Xi Wang(co-first author), Sen Wang, Feng Zhang, Lianhe Zhang, Yanxia Lei, Xiong Guo*. Is It the Appropriate Time to Stop Applying Selenium Enriched Salt in Kashin-Beck Disease Areas in China? Nutrients. 2015; 7:6195-6212.
