沈明望，男，西安交通大学医学部 公共卫生学院 流行病与卫生统计学系，副教授
电话：029-82655108
邮箱：mingwangshen521@xjtu.edu.cn
地址：陕西省西安市雁塔区雁塔西路76号，710061
教育背景:
2013.09-2017.12 西安交通大学 应用数学 博士；导师：肖燕妮
2011.09-2013.07西安交通大学 应用数学 硕博连读(硕士阶段）；导师：肖燕妮
2007.09-2011.07 河南师范大学 信息与计算科学 学士
出国经历:
2015.08-2017.08 美国德克萨斯大学奥斯汀分校 生物系 访问学者； 导师：Lauren Ancel Meyers
工作经历:
2018.01-2019.10 西安交通大学医学部 公共卫生学院 流行病与卫生统计学系 助理研究员/专职科研博士后；导师：庄贵华
2019.11-至今 西安交通大学医学部 公共卫生学院 流行病与卫生统计学系 副教授
研究领域:
理论流行病学、生物数学、人工智能在医学中的应用等交叉学科研究，具体包括艾滋病、肝炎、流感、麻疹、新冠等传染病以及癌症等慢性病的数学建模研究和卫生经济学评价。
获奖:
2016.04 第三届“徐宗本应用数学论文奖”一等奖
2021.04 西安交通大学第七届“十大学术新人”
2021.06 陕西省高校科协青年人才托举计划
承担科研项目:
1. 国家自然科学基金面上项目，基于新型防治措施的HIV跨尺度模型研究及数据分析，项目编号12171387，2022-2025年，51万元，在研，主持。
2. 国家自然科学基金青年基金项目，控制耐药型HIV产生及传播的多水平耦合模型研究，项目编号11801435，2019-2021年，25万元，在研，主持。
3. 中国博士后科学基金新冠肺炎疫情防控专项特别资助，新型冠状病毒肺炎传播的时空计量建模与防控措施的卫生经济学评价，项目编号2020T130095ZX，2020-2021年，18万元，在研，主持。
4. 中国博士后科学基金面上项目（一等资助），流感病毒在个体内演化和个体间传播的数学模型研究，项目编号2018M631134，2018-2021年，8万元，在研，主持。
5. 中央高校基本科研业务费专项资金资助(交叉类)，胃癌内镜筛查策略的动力学模型研究和成本效果分析，项目编号xjh012019055，2019-2021年，15万元，在研，主持。
6. 中央高校基本科研业务费专项资金资助(应急类)，基于传播动力学模型的新型冠状病毒肺炎防控策略研究和卫生经济学评价，项目编号xzy032020026，2020-2021年，10万元，已结题，主持。
7. 陕西省自然科学基础研究计划一般项目（青年），陕西省艾滋病暴露前药物预防的成本效果分析，项目编号2019JQ-187，2019-2021年，3万元，在研，主持。
8. 陕西省高校科协青年人才托举计划项目,基于动力学模型评估新冠疫苗接种对变异毒株传播的影响及成本效果，项目编号20210307，2022-2023年，1万元，在研，主持。
9. 盖茨基金会，新冠流行病学建模和风险评估，项目编号20200536，2020-2022年，10万美元，在研，参与。
10. 中国疾病预防控制中心性病艾滋病预防控制中心，HIV暴露前预防用药的卫生经济学效果评价及实现HIV扩大检测的卫生资源最优方案模型研究，项目编号20200344，2020-2021年，30.6万元，在研，参与。
11. 国家自然科学基金面上项目，我国乙肝病毒演化多样性的系统动力学模型与整合分析方法研究，项目编号11971375，2020-2023年，52万元，在研，参与。
12. 国家自然科学基金青年基金项目，个体异质性对艾滋病疫情传播与控制的影响研究，项目编号11701442，2018-2020年，25万元，已结题，参与。
13. 国家自然科学基金青年基金项目，组织-细胞多尺度耦合的实体肿瘤生长数学建模与算法研究，项目编号11601416，2017-2019年，18万元，已结题，参与。
14. 国家自然科学基金面上项目，Filippov系统在传染病动态控制中的应用研究，项目编号11571273，2016-2019年，50万元，已结题，参与。
参加会议:
1. 2017年5月22日—24日，参加在美国亚特兰大举办的“Models of Infectious Disease Agent Study (MIDAS)”会议，展览并解说以 “Early antiretroviral therapy and potent second-line drugs could decrease the transmission of drug resistance”为主题的海报。
2. 2018年6月23日-25日，参加在北京举办的第六届生物数学国际会议，作分会场报告“The cost-effectiveness of oral HIV pre-exposure prophylaxis and early antiretroviral treatment in the presence of drug resistance among men who have sex with men in San Francisco”。
3. 2018年10月25日-28日，参加在上海举办的第十二届中国卫生技术评估论坛，作分会场报告“中国胃癌筛查策略效应的数学模型研究”。
4. 2018年11月8日-11日，参加在西安举办的生物数学与医学大数据分析研讨会。
5. 2018年11月23日-26日，参加在西安举办的第二届“一带一路”全球健康国际研讨会暨丝绸之路大学联盟2018全球健康论坛。
6. 2018年12月14-15日，参加在广州举办的国际消除病毒性肝炎暨乙肝母婴零传播工程高峰论坛（第二届华南精准医学肝病论坛）。
7. 2019年4月12-14日，参加在西安举办的基于动力学不稳定性理论的健康临界状态评估方法专题研讨会。
8. 2019年5月19-24日，参加在美国佛罗里达州劳德代尔堡举办的第五届“Computational and Mathematical Population Dynamics (CMPD5)”国际会议，作分会场报告“Conflict and accord of optimal treatment strategies for HIV infection within and between hosts”。
9. 2019年6月12-13日，参加在成都举办的十三五项目“HIV耐药传播对艾滋病疫情影响的监测预警技术研究及应用”项目进展推进会，作大会报告“预测艾滋病耐药传播的数学模型研究”。
10. 2019年7月17-20日，参加在昆明举办的第八次全国流行病学学术会议。
11. 2019年9月13-16日，参加在西安举办的第三届“一带一路”全球健康国际研讨会暨丝绸之路大学联盟2019全球健康论坛。
12. 2019年9月28日，参加在西安举办的2019年西安生物数学研讨会。
13. 2019年10月20-11月15日，参加在天津医科大学举办的“教育部来华留学英语师资培训中心（医学）”第二十二期培训班（流行病学、医学统计学）。
14. 2019年11月22-24日，参加在北京举办的宫颈癌综合防控研究进展研讨会暨妇幼健康研究会宫颈癌防控研究专业委员会2019 年会议。
15. 2019年12月17日，参加在北京举办的国家重点研发项目“上消化道癌筛查和干预新型技术开发及评价研究”项目进展总结会。
16. 2020年9月19-20日，参加在西安举办的2020儿童肥胖防控—新冠肺炎疫情防控国际研讨会，作大会报告“基于传播动力学模型评估新冠防控措施的效果”。
17. 2020年9月26-27日，参加在西安举办的2020 传染病建模与数据分析国际研讨会。
18. 2020年11月7日，参加复旦大学在线举办的“全球化背景下新冠肺炎疫情的突发与应对：从公众健康到经济社会发展”全国博士后论坛，作分会场报告“基于数学模型评估湖北省封城措施对新冠在公共场所和家庭中传播的影响”。
19. 2020年11月7-8日，参加在西安举办的2020年微分方程及其应用研讨会。
20. 2020年11月14-15日，参加南开大学在线举办的新冠肺炎疫情建模与预测研讨会，作大会报告“不同社交距离和口罩使用下控制新冠疫情所需的疫苗效果和覆盖率研究”。
21. 2020年11月15日，参加在广州举办的2020年中国肿瘤学大会（2020CCO）中国抗癌协会癌症筛查与早诊早治专业委员会学术年会。
22. 2020年11月26-27日，参加在济南举办的“数学与科技”全国博士后学术论坛，作分会场报告“基于传播动力学模型评估控制新冠疫情所需的疫苗效果和覆盖率研究”。
23. 2020年12月8日，参加在北京举办的关于艾滋病防治的十三五科技重大专项子课题项目进展总结会。
24. 2021年4月11-13日，参加在北京举办的国家重点研发项目“上消化道癌筛查和干预新型技术开发及评价研究”课题总结大会。
25. 2021年4月17日，参加在西安举办的2021微分方程及其应用青年学者研讨会。
26. 2021年4月23-25日，参加在兰州举办的第三届生物数学建模与随机分析国际会议，作分会场报告“不同社交距离和口罩使用下控制新冠疫情所需的疫苗效果和覆盖率研究”。
27. 2021年5月14-16日，参加在西安举办的第三届跨学科行为健康会议暨中华预防医学会行为健康分会成立大会，作大会报告“数学模型评估健康行为在中外新冠疫情中的角色”。
28. 2021年7月22-25日，参加在荆州举办的第七届生物数学建模及其动力学分析国际研讨会，作分会场报告“基于人工智能辅助诊断筛查宫颈癌的成本效果分析”。
29. 2021年10月22-25日，参加在西安在线举办的2021年生物数学与数据分析前沿研讨会。
社会兼职:
1. 2019.07-至今 陕西省保健协会 专业委员会委员
2. 2020.11-至今 中国抗癌协会 癌症筛查与早诊早治专业委员会 青年委员
3. 2020.11-至今 中国抗癌协会 癌症筛查与早诊早治专业委员会 卫生经济学评价学组委员
指导学生:
1.2021.03 指导学生荣获第三十二届“腾飞杯”创新创业大赛创新赛道优秀奖。学生：刘俊杰、袁雪涛、刘彤、孟睿洁、蒋晶晶。
2.2021.07 指导学生荣获2021年 “国家级大学生创新训练项目”。学生：刘俊杰、欧宇航、雷江婕、赵轶龙、拓小凤。
发表论文:
已发表SCI论文41篇，其中第一作者14篇，共同一作3篇，通讯作者2篇，主要发表在BMC Medicine、Proceedings of the Royal Society B:Biological Sciences、Vaccine等杂志上(#表示共同一作，*表示共同通讯)。
2021年
1. Mingwang Shen#, Jian Zu#, Christopher K. Fairley, José A. Pagán, Bart Ferket, Bian Liu, Stella S. Yi, Earle Chambers, Guoqiang Li, Yuming Guo, Libin Rong, Yanni Xiao, Guihua Zhuang, Alexis Zebrowski, Brendan G. Carr, Yan Li*, Lei Zhang*. Effects of New York’s executive order on face mask use on COVID-19 infections and mortality: A modeling study. Journal of Urban Health. 2021, 98(2):197-204.
2. Mingwang Shen, Jian Zu, Christopher K. Fairley, José A. Pagán, Li An, Zhanwei Du, Yuming Guo, Libin Rong, Yanni Xiao, Guihua Zhuang, Yan Li*, Lei Zhang*. Projected COVID-19 epidemic in the United States in the context of the effectiveness of a potential vaccine and implications for social distancing and face mask use. Vaccine. 2021, 39(16):2295-2302.
3. Mingwang Shen, Yanni Xiao, Guihua Zhuang, Yan Li*, Lei Zhang*. Mass testing - an underexplored strategy for COVID-19 control. The Innovation. 2021, 2(2):100114.
4. Rui Li, Qian Li, Yiming Liu, Mingwang Shen*, Lei Zhang*, Guihua Zhuang*. Modeling the impact of Universal Influenza Vaccines on seasonal influenza with different subtypes. Epidemiology and Infection. 2021, https://doi.org/10.1017/S0950268821002284 .
5. Rui Li, Yan Li, Zhuoru Zou, Yiming Liu, Xinghui Li, Guihua Zhuang*, Mingwang Shen*, Lei Zhang*. Evaluating the Impact of SARS-CoV-2 Variants on the COVID-19 Epidemic and Social Restoration in the United States: A Mathematical Modelling Study. Frontiers in Public Health. 2021, 9:801763.
6. Jian Zu#, Mingwang Shen#, Christopher K Fairley, Miaolei Li, Guoqiang Li, Libin Rong, Yanni Xiao, Guihua Zhuang, Lei Zhang*, Yan Li*. Investigating the relationship between reopening the economy and implementing control measures during the COVID-19 pandemic. Public Health. 2021, 200:15-21.
7. Wenjun Wang#, Mingwang Shen#, Yusha Tao, Christopher K Fairley, Jason J Ong, Hui Chen, Qin Zhong, Zongren Li, Kai Zhang, Dawei Zhang, Feifei Yang, Sibing Zhang, Lei Zhang*, Kunlun He*. Elevated glucose level leads to rapid COVID-19 progression and high fatality. BMC Pulmonary Medicine. 2021, 21:64.
8. Zhuoru Zou, Christopher K Fairley, Mingwang Shen, Nick Scott, Xianglong Xu, Zengbin Li, Rui Li, Guihua Zhuang*, Lei Zhang*. Critical timing and extent of public health interventions to control outbreaks dominated by SARS-CoV-2 variants in Australia: a mathematical modelling study. International Journal of Infectious Diseases. 2021, https://doi.org/10.1016/j.ijid.2021.11.024 .
9. Ting Guo, Zhipeng Qiu, Mingwang Shen, Libin Rong*. Dynamics of a new HIV model with the activation status of infected cells. Journal of Mathematical Biology. 2021, 82:51.
10. Shi Zhao*, Mingwang Shen, Salihu S. Musa, Zihao Guo, Jinjun Ran*, Zhihang Peng, Yu Zhao, Marc K. C. Chong, Daihai He*, Maggie H. Wang. Inferencing superspreading potential using zero-truncated negative binomial model: exemplification with COVID-19. BMC Medical Research Methodology. 2021, 21:30.
11. Miaolei Li, Jian Zu*, Mingwang Shen, Guihua Zhuang, Siyuan Chen, Fuzhen Wang, Hui Zheng, Guomin Zhang*. Evaluating the independent influence of sexual transmission on HBV infection in China: a modeling study. BMC Public Health. 2021, 21:388.
12. Miaolei Li, Jian Zu*, Zongfang Li, Mingwang Shen, Yan Li, Fanpu Ji*. How to reduce the transmission risk of COVID-19 more effectively in New York City: An age-structured model study. Frontiers in Medicine. 2021, 8:641205.
13. Ruyi Xia, Hongmei Zeng, Wenjun Liu, Li Xie, Mingwang Shen, Peng Li, He Li, Wenqiang Wei, Wanqing Chen*, Guihua Zhuang*. Estimated cost-effectiveness of endoscopic screening for upper gastrointestinal tract cancer in high-risk areas in China. JAMA Network Open. 2021, 4(8):e2121403.
14. Lu Bai#, Haonan Lu#, Hailin Hu, M. Kumi Smith, Katherine Harripersaud, Veronika Lipkova, Yujin Wen, Xiuyan Guo, Wei Peng, Chenwei Liu, Mingwang Shen, Alfred Chixiong Shen, Lei Zhang*. Evaluation of work resumption strategies after COVID-19 reopening in the Chinese city of Shenzhen: a mathematical modeling study. Public Health. 2021, 193:17-22.
15. Li Ping Wong*, Qunhong Wu, Yanhua Hao, Xi Chen, Zhuo Chen, Haridah Alias, Mingwang Shen, Jingcen Hu, Shiwei Duan, Jinjie Zhang, Liyuan Han*. The role of institutional trust in preventive practices and treatment-seeking intention during the coronavirus disease 2019 outbreak among residents in Hubei, China. International Health. 2021, 1-9. https://doi.org/10.1093/inthealth/ihab023
16. Zhongxing Ding#, Kai Wang#, Mingwang Shen, Kai Wang, Shi Zhao, Wenyu Song, Rui Li, Zhongjie Li, Liping Wang, Ganzhu Feng, Zhiliang Hu, Hongxia Wei, Yanni Xiao, Changjun Bao, Jianli Hu, Liguo Zhu, Yong Li, Xufeng Chen, Yi Yin, Weiming Wang, Yongli Cai, Zhihang Peng*, Hongbing Shen*. Estimating the time interval between transmission generations and the presymptomatic period by contact tracing surveillance data from 31 provinces in the mainland of China. Fundamental Research. 2021, 1:104-110.
17. Xianglong Xu, Eric P F Chow, Mingwang Shen, Zhuoru Zou, Chongjian Wang, Jason J Ong, Christopher K Fairley, Lei Zhang*. Potential effect of antiseptic mouthwash on the incidence of Neisseria gonorrhoeae among men who have sex with men: a mathematical modelling study. BMJ Open. 2021,11:e052823.
18. Xianglong Xu, Eric P F Chow, Jason J Ong, Christian J P A Hoebe, Deborah Williamson, Mingwang Shen, Fabian Yuh Shiong Kong, Jane S Hocking, Christopher K Fairley, Lei Zhang*. Modelling the contribution that different sexual practices involving the oropharynx and saliva have on Neisseria gonorrhoeae infections at multiple anatomical sites in men who have sex with men. Sexually Transmitted Infections. 2021,97:183-189.
2020年
19. Mingwang Shen#, Zhihang Peng#, Yanni Xiao*, Guihua Zhuang*, Lei Zhang*. Modelling the epidemic trend of the 2019 novel coronavirus outbreak in China. The Innovation. 2020, 1(3):100048.
20. Mingwang Shen#, Zhihang Peng#, Yuming Guo, Libin Rong, Yan Li, Yanni Xiao*, Guihua Zhuang*, Lei Zhang*. Assessing the effects of metropolitan-wide quarantine on the spread of COVID-19 in public space and households. International Journal of Infectious Diseases. 2020, 96:503-505.
21. Mingwang Shen, Ruyi Xia, Zheng Luo, Hongmei Zeng, Wenqiang Wei, Guihua Zhuang*, Lei Zhang*, Wanqing Chen*. The long-term population impact of endoscopic screening programmes on disease burdens of gastric cancer in China: a mathematical modelling study. Journal of Theoretical Biology. 2020, 484:109996.
22. Ruina Liu#, Yuexi Gu#, Mingwang Shen#, Huan Li, Kai Zhang, Qi Wang, Xin Wei, Haohui Zhang, Di Wu, Kai Yu, Wumin Cai, Gongji Wang, Siruo Zhang, Qinru Sun*, Ping Huang* Zhenyuan Wang*. Predicting postmortem interval based on microbial community sequences and machine learning algorithms. Environmental Microbiology. 2020, 22(6): 2273-2291.
23. Siyu Liu, Mingwang Shen, Yingjie Bi*. Global asymptotic behavior for mixed vaccination strategy in a delayed epidemic model with interim-immune. Mathematical Biosciences and Engineering. 2020, 7(4):3601-3617.
24. Lei Zhang*, Mingwang Shen, Xiaomeng Ma, Shu Su, Jing Wang, Yusha Tao, Zhuoru Zou, Rui Zhao, Joseph Lau, Wenfeng Gong, Wei Li, Feng Liu, Kai Ye, Youfa Wang, Guihua Zhuang*, Christopher Fairley. What is required to prevent a second major outbreak of SARS-CoV-2 upon lifting quarantine in Wuhan City, China. The Innovation. 2020, 1(1):100006.
25. Lei Zhang*, Yusha Tao, Mingwang Shen, Christopher Fairley, Yuming Guo*. Can self-imposed prevention measures mitigate the COVID-19 epidemic? PLOS Medicine. 2020, 17(7):e1003240.
26. Lei Zhang*, Yusha Tao, Jing Wang, Jason J Ong, Weiming Tang, Maosheng Zou, Lu Bai, Miao Ding, Mingwang Shen, Guihua Zhuang*, Christopher Fairley. Early characteristics of the COVID-19 outbreak predict the subsequent epidemic scope. International Journal of Infectious Diseases. 2020, 97:219-224.
27. Jian Zu*, Miaolei Li, Zongfang Li, Mingwang Shen, Yanni Xiao, Fanpu Ji*. Transmission patterns of COVID-19 in the mainland of China and the efficacy of different control strategies: a data- and model-driven study. Infectious Diseases of Poverty. 2020, 9:83.
28. Xiaodan Sun#, Wenmin Yang#, Sanyi Tang, Mingwang Shen, Tianyang Wang, Qiuying Zhu, Zhiyong Shen, Shuai Tang, Huanhuan Chen, Yuhua Ruan*, Yanni Xiao*. Declining trend in HIV new infections in Guangxi, China: insights from linking reported HIV/AIDS cases with CD4-at-diagnosis data. BMC Public Health. 2020, 20:919.
29. Shu Su, Christopher K Fairley, Limin Mao, Nicholas Medland, Mingwang Shen, Yan Li, Guihua Zhuang, Lei Zhang*. Estimation of the impact of changing drug-use trend on HIV, hepatitis C and syphilis epidemics among people who use synthetic drug-only, polydrug and heroin-only during 2005-2035 in China: modelling study. Sexually Transmitted Infections. 2020, 96:608-614.
30. Jinli Liu, Zhen-Hu Ren, Hua Qiang, Jine Wu, Mingwang Shen, Lei Zhang*, Jun Lyu*. Trends in the incidence of diabetes mellitus: results from the Global Burden of Disease Study 2017 and implications for diabetes mellitus prevention. BMC Public Health. 2020, 20:1415.
2019年以前
31. Ruyi Xia, Shuliu Sun, Mingwang Shen, Lei Zhang, Guihua Zhuang*. Targeted hepatitis E vaccination for women of childbearing age is cost-effective in China. Vaccine. 2019, 37(39): 5868-5876.
32. Mingwang Shen, Yanni Xiao*, Libin Rong, Guihua Zhuang. Global dynamics and cost-effectiveness analysis of HIV pre-exposure prophylaxis and structured treatment interruptions based on a multi-scale model. Applied Mathematical Modelling. 2019, 75:162-200.
33. Xia Wang, Mingwang Shen, Yanni Xiao, Libin Rong*. Optimal control and cost-effectiveness analysis of a Zika virus infection model with comprehensive interventions. Applied Mathematics and Computation. 2019, 359:165-185.
34. Mingwang Shen, Yanni Xiao*, Libin Rong, Lauren Ancel Meyers. Conflict and accord of optimal treatment strategies for HIV infection within and between hosts. Mathematical Biosciences. 2019, 309:107-117.
35. Mingwang Shen, Yanni Xiao*, Libin Rong, Lauren Ancel Meyers, Steven E. Bellan. The cost-effectiveness of oral HIV pre-exposure prophylaxis and early antiretroviral treatment in the presence of drug resistance among men who have sex with men in San Francisco. BMC Medicine. 2018, 16:58.
36. Mingwang Shen, Yanni Xiao*, Libin Rong, Lauren Ancel Meyers, Steven E. Bellan. Early antiretroviral therapy and potent second-line drugs could decrease HIV incidence of drug resistance. Proceedings of the Royal Society B: Biological Sciences. 2017, 284(1857): 20170525.
37. Mingwang Shen, Yanni Xiao*. Global stability of a multi-group SVEIR epidemiological model with the vaccination age and infection age. Acta Applicandae Mathematicae. 2016, 144(1):137-157.
38. Mingwang Shen, Yanni Xiao*, Libin Rong. Modeling the effect of comprehensive interventions on Ebola virus transmission. Scientific Reports. 2015, 5:15818.
39. Mingwang Shen, Yanni Xiao*, Libin Rong. Global stability of an infection-age structured HIV-1 model linking within-host and between-host dynamics. Mathematical Biosciences. 2015, 263:37-50.
40. Mingwang Shen, Yanni Xiao*, Weike Zhou, Zhen Li. Global dynamics and applications of an epidemiological model for hepatitis C virus transmission in China. Discrete Dynamics in Nature and Society. 2015, Article ID 543029, 13 pages.
41. RA Cheke*, M-G Basáñez, M Perry, MT White, R Garms, E Obuobie, PHL Lamberton, S Young, MY Osei-Atweneboana, J Intsiful, Mingwang Shen, DA Boakye, MD Wilson. Potential effects of warmer worms and vectors on onchocerciasis transmission in West Africa. Philosophical Transactions of The Royal Society B: Biological Sciences. 2015, 370: 20130559.
Curriculum Vitae
Mingwang Shen, Male, Xi'an Jiaotong University, School of Public Health, Department of Epidemiology and Biostatistics, Associate Professor
Tel: 029-82655108
Email: mingwangshen521@xjtu.edu.cn
Address: No.76, Yanta West Road, Xi'an, Shaanxi, 710061, P.R. China
Education:
2011.09-2017.12 Xi’an Jiaotong University, PhD, Applied Mathematics; Supervisor: Yanni Xiao.
2007.09-2011.07 Henan Normal University, Bachelor, Computational Mathematics.
Work:
2015.08-2017.08 The University of Texas at Austin, Department of Integrative Biology, Visiting scholar, Epidemiology; Supervisor: Lauren Ancel Meyers.
2018.01-2019.10 Xi'an Jiaotong University, School of Public Health, Department of Epidemiology and Biostatistics, Post-doctor; Supervisor: Guihua Zhuang.
2019.11-Now Xi'an Jiaotong University, School of Public Health, Department of Epidemiology and Biostatistics, Associate Professor.
Research interest:
Theoretical epidemiology, Mathematical biology, AI in medicine, including mathematical modeling of HIV/AIDS, hepatitis, influenza, measles, and cost-effectiveness analysis of cancer screening, Non-communicable diseases, etc.
Awards:
2016.04 “Xu zongben Applied mathematics Award” (First prize)
Projects (leading):
1. National Natural Science Foundation of China，Research on the multi-level coupled model to control the emergence and transmission of drug resistant HIV，Grant number: 11801435，2019-2021，￥250,000.
2. China Postdoctoral Science Foundation Grant (First-class grant)，Mathematical modeling on the evolution of influenza virus at the within-host level and its spread at the between-host level，Grant number: 2018M631134，2018-2020，￥80,000.
3. The Fundamental Research Funds for the Central Universities, Dynamic modelling and cost-effectiveness analysis of endoscopic screening strategies for gastric cancer, Grant number: xjh012019055，2019-2021，￥150,000.
4. Natural Science Basic Research Program of Shaanxi Province，Cost-effectiveness analysis of HIV pre-exposure prophylaxis in Shaanxi Province, Grant number: 2019JQ-187, 2019-2020, ￥30,000.
International Conference:
1. “Early antiretroviral therapy and potent second-line drugs could decrease the transmission of drug resistance”,“Models of Infectious Disease Agent Study (MIDAS)”conference, 22-24th May, 2017, Atlanta, USA (Poster-presentation).
2. “The cost-effectiveness of oral HIV pre-exposure prophylaxis and early antiretroviral treatment in the presence of drug resistance among men who have sex with men in San Francisco”, 6th International Conference on Mathematical Biology, 23-25th June, 2018, Beijing, China (Oral-presentation).
3. “Conflict and accord of optimal treatment strategies for HIV infection within and between hosts”, 5th International Conference on Computational and Mathematical Population Dynamics (CMPD5), 19-24th May, 2019, Fort Lauderdale, Florida, USA (Oral-presentation).
Publications (peer-reviewed):
I have published 13 papers (SCI) as the first author on reputable journals, including BMC Medicine, Proceedings of the Royal Society B: Biological Sciences, Vaccine, etc.
2021
1. Mingwang Shen#, Jian Zu#, Christopher K. Fairley, José A. Pagán, Bart Ferket, Bian Liu, Stella S. Yi, Earle Chambers, Guoqiang Li, Yuming Guo, Libin Rong, Yanni Xiao, Guihua Zhuang, Alexis Zebrowski, Brendan G. Carr, Yan Li*, Lei Zhang*. Effects of New York’s executive order on face mask use on COVID-19 infections and mortality: A modeling study. Journal of Urban Health. 2021, https://doi.org/10.1007/s11524-021-00517-2.
2. Mingwang Shen#, Jian Zu, Christopher K. Fairley, José A. Pagán, Li An, Zhanwei Du, Yuming Guo, Libin Rong, Yanni Xiao, Guihua Zhuang, Yan Li*, Lei Zhang*. Projected COVID-19 epidemic in the United States in the context of the effectiveness of a potential vaccine and implications for social distancing and face mask use. Vaccine. 2021, https://doi.org/10.1016/j.vaccine.2021.02.056.
3. Wenjun Wang#, Mingwang Shen#, Yusha Tao, Christopher K Fairley, Jason J Ong, Hui Chen, Qin Zhong, Zongren Li, Kai Zhang, Dawei Zhang, Feifei Yang, Sibing Zhang, Lei Zhang*, Kunlun He*. Elevated glucose level leads to rapid COVID-19 progression and high fatality. BMC Pulmonary Medicine. 2021, 21:64.
4. Shi Zhao*, Mingwang Shen, Salihu S. Musa, Zihao Guo, Jinjun Ran*, Zhihang Peng, Yu Zhao, Marc K. C. Chong, Daihai He*, Maggie H. Wang. Inferencing superspreading potential using zero-truncated negative binomial model: exemplification with COVID-19. BMC Medical Research Methodology. 2021, 21:30.
5. Miaolei Li, Jian Zu#, Mingwang Shen, Guihua Zhuang, Siyuan Chen, Fuzhen Wang, Hui Zheng, Guomin Zhang#. Evaluating the independent influence of sexual transmission on HBV infection in China: a modeling study. BMC Public Health. 2021, 21:388.
6. Lu Bai#, Haonan Lu#, Hailin Hu, M. Kumi Smith, Katherine Harripersaud, Veronika Lipkova, Yujin Wen, Xiuyan Guo, Wei Peng, Chenwei Liu, Mingwang Shen, Alfred Chixiong Shen, Lei Zhang*. Evaluation of work resumption strategies after COVID-19 reopening in the Chinese city of Shenzhen: a mathematical modeling study. Public Health. 2021, in press.
2020
7. Mingwang Shen#, Zhihang Peng#, Yanni Xiao*, Guihua Zhuang*, Lei Zhang*. Modelling the epidemic trend of the 2019 novel coronavirus outbreak in China. The Innovation. 2020, 1(3):100048.
8. Mingwang Shen#, Zhihang Peng#, Yuming Guo, Libin Rong, Yan Li, Yanni Xiao*, Guihua Zhuang*, Lei Zhang*. Assessing the effects of metropolitan-wide quarantine on the spread of COVID-19 in public space and households. International Journal of Infectious Diseases. 2020, 96:503-505.
9. Mingwang Shen, Ruyi Xia, Zheng Luo, Hongmei Zeng, Wenqiang Wei, Guihua Zhuang*, Lei Zhang*, Wanqing Chen*. The long-term population impact of endoscopic screening programmes on disease burdens of gastric cancer in China: a mathematical modelling study. Journal of Theoretical Biology. 2020, 484:109996.
10. Ruina Liu#, Yuexi Gu#, Mingwang Shen#, Huan Li, Kai Zhang, Qi Wang, Xin Wei, Haohui Zhang, Di Wu, Kai Yu, Wumin Cai, Gongji Wang, Siruo Zhang, Qinru Sun*, Ping Huang* Zhenyuan Wang*. Predicting postmortem interval based on microbial community sequences and machine learning algorithms. Environmental Microbiology. 2020, 22(6): 2273-2291.
11. Siyu Liu, Mingwang Shen, Yingjie Bi*. Global asymptotic behavior for mixed vaccination strategy in a delayed epidemic model with interim-immune. Mathematical Biosciences and Engineering. 2020, 7(4):3601-3617.
12. Lei Zhang*, Mingwang Shen, Xiaomeng Ma, Shu Su, Jing Wang, Yusha Tao, Zhuoru Zou, Rui Zhao, Joseph Lau, Wenfeng Gong, Wei Li, Feng Liu, Kai Ye, Youfa Wang, Guihua Zhuang*, Christopher Fairley. What is required to prevent a second major outbreak of SARS-CoV-2 upon lifting quarantine in Wuhan City, China. The Innovation. 2020, 1(1):100006.
13. Lei Zhang*, Yusha Tao, Mingwang Shen, Christopher Fairley, Yuming Guo*. Can self-imposed prevention measures mitigate the COVID-19 epidemic? PLOS Medicine. 2020, 17(7):e1003240.
14. Lei Zhang*, Yusha Tao, Jing Wang, Jason J Ong, Weiming Tang, Maosheng Zou, Lu Bai, Miao Ding, Mingwang Shen, Guihua Zhuang*, Christopher Fairley. Early characteristics of the COVID-19 outbreak predict the subsequent epidemic scope. International Journal of Infectious Diseases. 2020, 97:219-224.
15. Jian Zu*, Miaolei Li, Zongfang Li, Mingwang Shen, Yanni Xiao, Fanpu Ji*. Transmission patterns of COVID-19 in the mainland of China and the efficacy of different control strategies: a data- and model-driven study. Infectious Diseases of Poverty. 2020, 9:83.
16. Xiaodan Sun#, Wenmin Yang#, Sanyi Tang, Mingwang Shen, Tianyang Wang, Qiuying Zhu, Zhiyong Shen, Shuai Tang, Huanhuan Chen, Yuhua Ruan*, Yanni Xiao*. Declining trend in HIV new infections in Guangxi, China: insights from linking reported HIV/AIDS cases with CD4-at-diagnosis data. BMC Public Health. 2020, 20:919.
17. Shu Su, Christopher K Fairley, Limin Mao, Nicholas Medland, Mingwang Shen, Yan Li, Guihua Zhuang, Lei Zhang*. Estimation of the impact of changing drug-use trend on HIV, hepatitis C and syphilis epidemics among people who use synthetic drug-only, polydrug and heroin-only during 2005-2035 in China: modelling study. Sexually Transmitted Infections. 2020,1-7.
18. Xianglong Xu, Eric P F Chow, Jason J Ong, Christian J P A Hoebe, Deborah Williamson, Mingwang Shen, Fabian Yuh Shiong Kong, Jane S Hocking, Christopher K Fairley, Lei Zhang*. Modelling the contribution that different sexual practices involving the oropharynx and saliva have on Neisseria gonorrhoeae infections at multiple anatomical sites in men who have sex with men. Sexually Transmitted Infections. 2020,1-7.
19. Jinli Liu, Zhen-Hu Ren, Hua Qiang, Jine Wu, Mingwang Shen, Lei Zhang*, Jun Lyu*. Trends in the incidence of diabetes mellitus: results from the Global Burden of Disease Study 2017 and implications for diabetes mellitus prevention. BMC Public Health. 2020, 20:1415.
Pre-2019
20. Ruyi Xia, Shuliu Sun, Mingwang Shen, Lei Zhang, Guihua Zhuang*. Targeted hepatitis E vaccination for women of childbearing age is cost-effective in China. Vaccine. 2019, 37(39): 5868-5876.
21. Mingwang Shen, Yanni Xiao*, Libin Rong, Guihua Zhuang. Global dynamics and cost-effectiveness analysis of HIV pre-exposure prophylaxis and structured treatment interruptions based on a multi-scale model. Applied Mathematical Modelling. 2019, 75:162-200.
22. Xia Wang, Mingwang Shen, Yanni Xiao, Libin Rong*. Optimal control and cost-effectiveness analysis of a Zika virus infection model with comprehensive interventions. Applied Mathematics and Computation. 2019, 359:165-185.
23. Mingwang Shen, Yanni Xiao*, Libin Rong, Lauren Ancel Meyers. Conflict and accord of optimal treatment strategies for HIV infection within and between hosts. Mathematical Biosciences. 2019, 309:107-117.
24. Mingwang Shen, Yanni Xiao*, Libin Rong, Lauren Ancel Meyers, Steven E. Bellan. The cost-effectiveness of oral HIV pre-exposure prophylaxis and early antiretroviral treatment in the presence of drug resistance among men who have sex with men in San Francisco. BMC Medicine. 2018, 16:58.
25. Mingwang Shen, Yanni Xiao*, Libin Rong, Lauren Ancel Meyers, Steven E. Bellan. Early antiretroviral therapy and potent second-line drugs could decrease HIV incidence of drug resistance. Proceedings of the Royal Society B: Biological Sciences. 2017, 284(1857): 20170525.
26. Mingwang Shen, Yanni Xiao*. Global stability of a multi-group SVEIR epidemiological model with the vaccination age and infection age. Acta Applicandae Mathematicae. 2016, 144(1):137-157.
27. Mingwang Shen, Yanni Xiao*, Libin Rong, Modeling the effect of comprehensive interventions on Ebola virus transmission. Scientific Reports. 2015, 5:15818.
28. Mingwang Shen, Yanni Xiao*, Libin Rong. Global stability of an infection-age structured HIV-1 model linking within-host and between-host dynamics. Mathematical Biosciences. 2015, 263:37-50.
29. Mingwang Shen, Yanni Xiao*, Weike Zhou, Zhen Li. Global dynamics and applications of an epidemiological model for hepatitis C virus transmission in China. Discrete Dynamics in Nature and Society. 2015, Article ID 543029, 13 pages.
30. RA Cheke*, M-G Basáñez, M Perry, MT White, R Garms, E Obuobie, PHL Lamberton, S Young, MY Osei-Atweneboana, J Intsiful, Mingwang Shen, DA Boakye, MD Wilson. Potential effects of warmer worms and vectors on onchocerciasis transmission in West Africa. Philosophical Transactions of The Royal Society B: Biological Sciences. 2015, 370: 20130559.
教育背景:
2013.09-2017.12 西安交通大学 应用数学 博士；导师：肖燕妮
2011.09-2013.07西安交通大学 应用数学 硕博连读(硕士阶段）；导师：肖燕妮
2007.09-2011.07 河南师范大学 信息与计算科学 学士
出国经历:
2015.08-2017.08 美国德克萨斯大学奥斯汀分校 生物系 访问学者；
导师：Lauren Ancel Meyers
工作经历:
2018.01-2019.10 西安交通大学医学部 公共卫生学院 流行病与卫生统计学系 助理研究员/专职科研博士后；导师：庄贵华
2019.11-至今 西安交通大学医学部 公共卫生学院 流行病与卫生统计学系 副教授
研究领域:
理论流行病学、生物数学、人工智能在医学中的应用等交叉学科研究，具体包括艾滋病、肝炎、流感、麻疹等传染病以及癌症等慢性病的数学建模研究和卫生经济学评价。
获奖:
2016.04 “徐宗本应用数学论文奖”一等奖
承担科研项目:
1.国家自然科学基金青年基金项目，控制耐药型HIV产生及传播的多水平耦合模型研究，项目编号11801435，2019-2021年，25万元，在研，主持。
2.中国博士后科学基金面上项目（一等资助），流感病毒在个体内演化和个体间传播的数学模型研究，项目编号2018M631134，2018-2020年，8万元，在研，主持。
3.中央高校基本科研业务费专项资金资助，胃癌内镜筛查策略的动力学模型研究和成本效果分析，项目编号xjh012019055，2019-2021年，15万元，在研，主持。
4.陕西省自然科学基础研究计划一般项目（青年），陕西省艾滋病暴露前药物预防的成本效果分析，项目编号2019JQ-187，2019-2021年，3万元，在研，主持。
5.国家自然科学基金面上项目，我国乙肝病毒演化多样性的系统动力学模型与整合分析方法研究，项目编号11971375，2020-2023年，52万元，在研，参与。
6.国家自然科学基金青年基金项目，个体异质性对艾滋病疫情传播与控制的影响研究，项目编号11701442，2018-2020年，25万元，在研，参与。
7.国家自然科学基金青年基金项目，组织-细胞多尺度耦合的实体肿瘤生长数学建模与算法研究，项目编号11601416，2017-2019年，18万元，已结题，参与。
8.国家自然科学基金面上项目，Filippov系统在传染病动态控制中的应用研究，项目编号11571273，2016-2019年，50万元，已结题，参与。
参加会议:
1.2017年5月22日—24日，参加在美国亚特兰大举办的“Models of Infectious Disease Agent Study (MIDAS)”会议，展览并解说以 “Early antiretroviral therapy and potent second-line drugs could decrease the transmission of drug resistance”为主题的海报。
2.2018年6月23日-25日，参加在北京举办的第六届生物数学国际会议，作分会场报告“The cost-effectiveness of oral HIV pre-exposure prophylaxis and early antiretroviral treatment in the presence of drug resistance among men who have sex with men in San Francisco”。
3.2018年10月25日-28日，参加在上海举办的第十二届中国卫生技术评估论坛，作分会场报告“中国胃癌筛查策略效应的数学模型研究”。
4.2018年11月8日-11日，参加在西安举办的生物数学与医学大数据分析研讨会。
5.2018年11月23日-26日，参加在西安举办的第二届“一带一路”全球健康国际研讨会暨丝绸之路大学联盟2018全球健康论坛。
6.2018年12月14-15日，参加在广州举办的国际消除病毒性肝炎暨乙肝母婴零传播工程高峰论坛（第二届华南精准医学肝病论坛）。
7.2019年4月12-14日，参加在西安举办的基于动力学不稳定性理论的健康临界状态评估方法专题研讨会。
8.2019年5月19-24日，参加在美国佛罗里达州劳德代尔堡举办的第五届“Computational and Mathematical Population Dynamics (CMPD5)”国际会议，作分会场报告“Conflict and accord of optimal treatment strategies for HIV infection within and between hosts”。
9.2019年6月12-13日，参加在成都举办的十三五项目“HIV耐药传播对艾滋病疫情影响的监测预警技术研究及应用”项目进展推进会，作大会报告“预测艾滋病耐药传播的数学模型研究”。
10.2019年7月17-20日，参加在昆明举办的第八次全国流行病学学术会议。
11.2019年9月13-16日，参加在西安举办的第三届“一带一路”全球健康国际研讨会暨丝绸之路大学联盟2019全球健康论坛。
12.2019年9月28日，参加在西安举办的2019年西安生物数学研讨会。
13.2019年10月20-11月15日，参加在天津医科大学举办的“教育部来华留学英语师资培训中心（医学）”第二十二期培训班（流行病学、医学统计学）。
14.2019年11月22-24日，参加在北京举办的宫颈癌综合防控研究进展研讨会暨妇幼健康研究会宫颈癌防控研究专业委员会2019 年会议。
15.2019年12月17日，参加在北京举办的国家重点研发项目“上消化道癌筛查和干预新型技术开发及评价研究”项目进展总结会。
社会兼职:
1.2019.07-至今 陕西省保健协会专业委员会委员
2.2018.11-至今 中国抗癌协会会员
发表论文:
已发表SCI论文12篇，其中第一作者9篇，主要发表在BMC Medicine(IF=9.088)、Proceedings of the Royal Society B:Biological Sciences(IF=4.85) 等杂志上。
1.Mingwang Shen, Ruyi Xia, Zheng Luo, Hongmei Zeng, Wenqiang Wei, Guihua Zhuang*, Lei Zhang*, Wanqing Chen*. The long-term population impact of endoscopic screening programmes on disease burdens of gastric cancer in China: a mathematical modelling study,Journal of Theoretical Biology.2020, 484:109996.
2.Ruyi Xia, Shuliu Sun,Mingwang Shen,Lei Zhang, Guihua Zhuang.Targeted hepatitis E vaccination for women of childbearing age is cost-effective in China,Vaccine. 2019,37(39): 5868-5876.
3.Mingwang Shen, Yanni Xiao*, Libin Rong, Guihua Zhuang. Global dynamics and cost-effectiveness analysis of HIV pre-exposure prophylaxis and structured treatment interruptions based on a multi-scale model,Applied Mathematical Modelling. 2019, 75:162-200.
4.Xia Wang,Mingwang Shen, Yanni Xiao, Libin Rong*. Optimal control and cost-effectiveness analysis of a Zika virus infection model with comprehensive interventions,Applied Mathematics and Computation. 2019, 359:165-185.
5.Mingwang Shen, Yanni Xiao*, Libin Rong, Lauren Ancel Meyers. Conflict and accord of optimal treatment strategies for HIV infection within and between hosts,Mathematical Biosciences.2019, 309:107-117.
6.Mingwang Shen, Yanni Xiao*, Libin Rong, Lauren Ancel Meyers, Steven E. Bellan. The cost-effectiveness of oral HIV pre-exposure prophylaxis and early antiretroviral treatment in the presence of drug resistance among men who have sex with men in San Francisco,BMC Medicine.2018, 16:58.
7.Mingwang Shen, Yanni Xiao*, Libin Rong, Lauren Ancel Meyers, Steven E. Bellan. Early antiretroviral therapy and potent second-line drugs could decrease HIV incidence of drug resistance,Proceedings of the Royal Society B: Biological Sciences.2017, 284(1857): 20170525.
8.Mingwang Shen, Yanni Xiao*. Global stability of a multi-group SVEIR epidemiological model with the vaccination age and infection age,Acta Applicandae Mathematicae. 2016, 144(1):137-157.
9.Mingwang Shen, Yanni Xiao*, Libin Rong, Modeling the effect of comprehensive interventions on Ebola virus transmission,Scientific Reports.2015, 5:15818.
10.Mingwang Shen, Yanni Xiao*, Libin Rong. Global stability of an infection-age structured HIV-1 model linking within-host and between-host dynamics,Mathematical Biosciences. 2015, 263:37-50.
11.Mingwang Shen, Yanni Xiao*, Weike Zhou, Zhen Li. Global dynamics and applications of an epidemiological model for hepatitis C virus transmission in China,Discrete Dynamics in Nature and Society. 2015, Article ID 543029, 13 pages.
12.RA Cheke*, M-G Basáñez, M Perry, MT White, R Garms, E Obuobie, PHL Lamberton, S Young, MY Osei-Atweneboana, J Intsiful,Mingwang Shen, DA Boakye, MD Wilson. Potential effects of warmer worms and vectors on onchocerciasis transmission in West Africa,Philosophical Transactions of The Royal Society B: Biological Sciences. 2015, 370: 20130559.
